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World of medicine shaken: The disease that is aging teenagers, scientists react

  • 6 hours ago
  • 1 min read

Scientists have identified a new genetic disease that causes premature aging in teenagers, raising concerns about its impact on physical development and brain function.


The study was conducted by the Sanford Burnham Prebys Institute in collaboration with an international team and was published in the scientific journal *Nature Communications*. According to the research, affected patients show symptoms similar to progeria, such as early greying and signs of accelerated aging, but in this case it involves a previously unknown condition.


Initially, researchers focused on a group of teenagers who presented symptoms resembling progeria. However, further analysis revealed that in addition to physical changes, the patients also had neurological problems and a progressive loss of motor and intellectual abilities, indicating a different disorder.


To identify the cause, scientists used advanced techniques, including genome sequencing to detect DNA mutations. They identified a change in the INVS1ABP gene, which appears to play a key role in the development of the disease.


Researchers also used cellular reprogramming methods, taking skin cells from patients and turning them into stem cells. This allowed them to observe in the laboratory how the mutation affects brain cells.


The results showed that affected cells develop more slowly and retain the mutation, helping scientists better understand the mechanism of the disease.

"KORÇA BOOM"


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